Journal of Cardiovascular Computed Tomography
Volume 1, Issue 1 , Pages 3-20 , July 2007

Cardiac CT: State of the art for the detection of coronary arterial stenosis

Received 14 March 2007 ,Accepted 19 April 2007.

References 

  1. Agatston AS, Janowitz WR, Hildner FJ, Zusmer NR, Viamonte M, Detrano R. Quantification of coronary artery calcium using ultrafast computed tomography. J Am Coll Cardiol. 1990;15:827–832
  2. Moshage WE, Achenbach S, Seese B, Bachmann K, Kirchgeorg M. Coronary artery stenoses: three-dimensional imaging with electrocardiographically triggered, contrast agent-enhanced, electron-beam CT. Radiology. 1995;196:707–714
  3. Achenbach S, Moshage W, Ropers D, Nossen J, Daniel WG. Value of electron-beam computed tomography for the noninvasive detection of high-grade coronary-artery stenoses and occlusions. N Engl J Med. 1998;339:1964–1971
  4. Schmermund A, Rensing BJ, Sheedy PF, Bell MR, Rumberger JA. Intravenous electron-beam computed tomographic coronary angiography for segmental analysis of coronary artery stenoses. J Am Coll Cardiol. 1998;31:1547–1554
  5. Reddy G, Chernoff DM, Adams JR, Higgins CB. Coronary artery stenoses: assessment with contrast-enhanced electron-beam CT and axial reconstructions. Radiology. 1998;208:167–172
  6. Rensing BJ, Bongaerts A, van Geuns RJ, van Ooijen P, Oudkerk M, de Feyter P. Intravenous coronary angiography by electron beam computed tomography (A clinical evaluation). Circulation. 1998;98:2509–2512
  7. Budoff MJ, Oudiz RJ, Zalace CP, Bakhsheshi H, Goldberg SL, French WJ, et al. Intravenous three-dimensional coronary angiography using contrast-enhanced electron beam computed tomography. Am J Cardiol. 1999;83:840–845
  8. Kachelriess M, Ulzheimer S, Kalender WA. ECG-correlated image reconstruction from subsecond multi-slice spiral CT scans of the heart. Med Phys. 2000;27:1881–1902
  9. Ohnesorge B, Flohr T, Becker C, Kopp AF, Schoepf UJ, Baum U, et al. Cardiac imaging by means of electrocardiographically gated multisection spiral CT: initial experience. Radiology. 2000;217:564–571
  10. Achenbach S, Ulzheimer S, Baum U, Kachelriess M, Ropers D, Giesler T, et al. Noninvasive coronary angiography by retrospectively ECG-gated multislice spiral CT. Circulation. 2000;102:2823–2828
  11. Nieman K, Oudkerk M, Rensing BJ, van Ooijen P, Munne A, van Geuns RJ, et al. Coronary angiography with multi-slice computed tomography. Lancet. 2001;357:599–603
  12. Achenbach S, Giesler T, Ropers D, Ulzheimer S, Derlien H, Schulte C, et al. Detection of coronary artery stenoses by contrast-enhanced, retrospectively electrocardiographically-gated, multislice spiral computed tomography. Circulation. 2001;103:2535–2538
  13. Kondo C, Mori S, Endo M, Kusakabe K, Suzuki N, Hattori A, et al. Real-time volumetric imaging of human heart without electrocardiographic gating by 256-detector row computed tomography: initial experience. J Comput Assist Tomogr. 2005;29:694–698
  14. Mori S, Kondo C, Suzuki N, Hattori A, Kusakabe M, Endo M. Volumetric coronary angiography using the 256-detector row computed tomography scanner: comparison in vivo and in vitro with porcine models. Acta Radiol. 2006;47:186–191
  15. Flohr TG, McCollough CH, Bruder H, Petersilka M, Gruber K, Suss C, et al. First performance evaluation of a dual-source CT (DSCT) system. Eur Radiol. 2006;16:256–268
  16. Achenbach S, Ropers D, Kuettner A, Flohr T, Ohnesorge B, Bruder H, et al. Contrast-enhanced coronary artery visualization by dual-source computed tomography--initial experience. Eur J Radiol. 2006;57:331–335
  17. Johnson TR, Nikolaou K, Wintersperger BJ, Leber AW, von Ziegler F, Rist C, et al. Dual-source CT cardiac imaging: initial experience. Eur Radiol. 2006;16:1409–1415
  18. Scheffel H, Alkadhi H, Plass A, Vachenauer R, Desbiolles L, Gaemperli O, et al. Accuracy of dual-source CT coronary angiography: first experience in a high pre-test probability population without heart rate control. Eur Radiol. 2006;16:2739–2747
  19. Nieman K, Cademartiri F, Lemos PA, Raaijmakers R, Pattynama PM, de Feyter PJ. Reliable noninvasive coronary angiography with fast submillimeter multislice spiral computed tomography. Circulation. 2002;106:2051–2054
  20. Ropers D, Baum U, Pohle K, Anders K, Ulzheimer S, Ohnesorge B, et al. Detection of coronary artery stenoses with thin-slice multi-detector row spiral computed tomography and multiplanar reconstruction. Circulation. 2003;107:664–666
  21. Kuettner A, Trabold T, Schroeder S, Feyer A, Beck T, Brueckner A, et al. Noninvasive detection of coronary lesions using 16-detector multislice spiral computed tomography technology (Initial Clinical Results). J Am Coll Cardiol. 2004;44:1230–1237
  22. Mollet NR, Cademartiri F, Nieman K, Saia F, Lemos PA, McFadden EP, et al. Multislice spiral computed tomography coronary angiography in patients with stable angina pectoris. J Am Coll Cardiol. 2004;43:2265–2270
  23. Martuscelli E, Romagnoli A, D’Eliseo A, Razzini C, Tomassini M, Sperandio M, et al. Accuracy of thin-slice computed tomography in the detection of coronary stenoses. Eur Heart J. 2004;25:1043–1048
  24. Fine JJ, Hopkins CB, Hall BAX, Delphie RE, Atteberry TW, Newton C. Noninvasive coronary angiography: agreement of multi-slice spiral computed tomography and selective catheter angiography. Int J Cardiovasc Imaging. 2004;20:549–552
  25. Kaiser C, Bremerich J, Haller S, Brunner-La Roca HP, Bongartz G, Pfisterer M, et al. Limited diagnostic yield of non-invasive coronary angiography by 16-slice multidetector spiral computed tomography in routine patients referred for evaluation of coronary artery disease. Eur Heart J. 2005;26:1987–1992
  26. Aviram G, Finkelstein A, Herz I, Lessick J, Miller H, Graif M, et al. Clinical value of 16-slice multi-detector CT compared to invasive coronary angiography. Int J Cardiovasc Intervent. 2005;7:21–28
  27. Hoffmann U, Moselewski F, Cury RC, Ferencik M, Jang IK, Diaz LJ, et al. Predictive value of 16-slice multidetector spiral computed tomography to detect significant obstructive coronary artery disease in patients at high risk for coronary artery disease: patient-versus segment-based analysis. Circulation. 2004;110:2638–2643
  28. Kuettner A, Beck T, Drosch T, Kettering K, Heuschmid M, Burgstahler C, et al. Image quality and diagnostic accuracy of non-invasive coronary imaging with 16-detector slice spiral computed tomography with 188 ms temporal resolution. Heart. 2005;91:938–941
  29. Mollet NR, Cademartiri F, Krestin GP, McFadden EP, Arampatzis CA, Serruys PW, et al. Improved diagnostic accuracy with 16-row multi-slice computed tomography coronary angiography. J Am Coll Cardiol. 2005;45:128–132
  30. Morgan-Hughes GJ, Roobottom CA, Owens PE, Marshall AJ. Highly accurate coronary angiography with submillimetre, 16 slice computed tomography. Heart. 2005;91:308–313
  31. Schuijf JD, Bax JJ, Salm LP, Jukema JW, Lanb HJ, van der Wall EE, et al. Noninvasive coronary imaging and assessment of left ventricular function using 16-slice computed tomography. Am J Cardiol. 2005;95:57177–4
  32. Hoffmann MHK, Shi H, Schmitz BL, Schmid FT, Lieberknecht M, Schulze R, et al. Noninvasive coronary angiography with multislice computed tomography. JAMA. 2005;293:2471–2478
  33. Achenbach S, Ropers D, Pohle FK, Raaz D, von Erffa J, Yilmaz A, et al. Detection of coronary artery stenoses using multi-detector CT with 16x0.75 mm collimation and 375 ms rotation. Eur Heart J. 2005;26:1978–1986
  34. Garcia MJ, Lessick J, Hoffmann MH CATSCAN Study Investigators. Accuracy of 16-row multidetector computed tomography for the assessment of coronary artery stenosis. JAMA. 2006;296:403–411
  35. Dewey M, Teige F, Schnappauf D, Laule M, Borges AC, Wernecke KD, et al. Noninvasive detection of coronary artery stenoses with multislice computed tomography or magnetic resonance imaging. Ann Intern Med. 2006;145:407–415
  36. Cordeiro MAS, Miller JM, Schmidt A, Lardo AC, Rosen BD, Bush DE, et al. Noninvasive half-millimeter 32-detector-row CT angiography accurately excludes significant stenoses in patients with advanced coronary artery disease and high calcium scores. Heart. 2006;92:589–597
  37. Lim MCL, Wong TW, Yaneza LO, De Larrazabal C, Lau JK, Boey HK. Non-invasive detection of significant coronary artery disease with multi-section computed tomography angiography in patients with suspected coronary artery disease. Clin Radiol. 2006;61:174–180
  38. Leschka S, Alkadhi H, Plass A, Desbiolles L, Grünenfelder J, Marincek B, et al. Accuracy of MSCT coronary angiography with 64-slice technology: first experience. Eur Heart J. 2005;26:1482–1487
  39. Raff GJ, Gallagher MJ, O’Neill WW, Goldstein JA. Diagnostic accuracy of noninvasive angiography using 64-slice spiral computed tomography. J Am Coll Cardiol. 2005;46:552–557
  40. Leber AW, Knez A, von Ziegler F, Becker A, Nikolaou K, Paul S, et al. Quantification of obstructive and nonobstructive coronary lesions by 64-slice computed tomography (A comparative study with quantitative coronary angiography and intravascular ultrasound). J Am Coll Cardiol. 2005;46:147–154
  41. Mollet NR, Cademartiri F, van Mieghem CA, Runza G, McFadden EP, Baks T, et al. High-resolution spiral computed tomography coronary angiography in patients referred for diagnostic conventional coronary angiography. Circulation. 2005;112:2318–2323
  42. Ropers D, Rixe J, Anders K, Küttner A, Baum U, Bautz W, et al. Usefulness of multidetector row computed tomography with 64 x 0.6 mm collimation and 330-ms rotation for the noninvasive detection of significant coronary artery stenoses. Am J Cardiol. 2006;97:343–348
  43. Fine JJ, Hopkins CB, Ruff N, Newton FC. Comparison of accuracy of 64-slice cardiovascular computed tomography with coronary angiography in patients with suspected coronary artery disease. Am J Cardiol. 2006;97:173–174
  44. Nikolaou K, Knez A, Rist C, Wintersperger BJ, Leber A, Johnson T, et al. Accuracy of 64-MDCT in the diagnosis of ischemic heart disease. AJR Am J Roentgenol. 2006;187:111–117
  45. Ghostine S, Caussin C, Larchez C, Ghostine S, Pesenti-Rossi D, Daoud B, et al. Comparison of coronary minimal lumen area quantification by sixty-four-slice computed tomography versus intravascular ultrasound for intermediate stenosis. Am J Cardiol. 2006;98:871–876
  46. Meijboom WB, Mollet NR, Van Mieghem CA, Kluin J, Weustink AC, Pugliese F, et al. Pre-operative computed tomography coronary angiography to detect significant coronary artery disease in patients referred for cardiac valve surgery. J Am Coll Cardiol. 2006;48:1658–1665
  47. Hoffmann U, Nagurney JT, Moselewski F, Pena A, Ferencik M, Chae CU, et al. Coronary multidetector computed tomography in the assessment of patients with acute chest pain. Circulation. 2006;114:2251–2260
  48. Gallagher MJ, Ross MA, Raff GL, Goldstein JA, O’Neill WW, O’Neil B. The diagnostic accuracy of 64-slice computed tomography coronary angiography compared with stress nuclear imaging in emergency department low-risk chest pain patients. Ann Emerg Med. 2007;49:125–136
  49. Goldstein JA, Gallagher MJ, O’Neill WW, Ross MA, O’Neil BJ, Raff GL. A randomized controlled trial of multi-slice coronary computed tomography for evaluation of acute chest pain. J Am Coll Cardiol. 2007;49:863–871
  50. Budoff MJ, Achenbach S, Blumenthal RS, Carr JJ, Goldin JG, Greenland P, et al. Assessment of coronary artery disease by cardiac computed tomography: a scientific statement from the American Heart Association Committee on Cardiovascular Imaging and Intervention, Council on Cardiovascular Radiology and Intervention, and Committee on Cardiac Imaging, Council on Clinical Cardiology. Circulation. 2006;114:1761–1791
  51. Hendel RC, Patel MR, Kramer CM, Poon M, Hendel RC, Carr JC, et al. ACCF/ACR/SCCT/SCMR/ASNC/NASCI/SCAI/SIR 2006 appropriateness criteria for cardiac computed tomography and cardiac magnetic resonance imaging: a report of the American College of Cardiology Foundation Quality Strategic Directions Committee Appropriateness Criteria Working Group, American College of Radiology, Society of Cardiovascular Computed Tomography, Society for Cardiovascular Magnetic Resonance, American Society of Nuclear Cardiology, North American Society for Cardiac Imaging, Society for Cardiovascular Angiography and Interventions, and Society of Interventional Radiology. J Am Coll Cardiol. 2006;48:1475–1497
  52. Mahnken AH, Muhlenbruch G, Seyfarth T, Flohr T, Stanzel S, Wildberger JE, et al. 64-slice computed tomography assessment of coronary artery stents: a phantom study. Acta Radiol. 2006;47:36–42
  53. Maintz D, Seifarth H, Raupach R, Flohr T, Rink M, Sommer T, et al. 64-slice multidetector coronary CT angiography: in vitro evaluation of 68 different stents. Eur Radiol. 2006;16:818–826
  54. Gilard M, Cornily JC, Pennec PY, Le Gal G, Nonent M, Mansourati J, et al. Assessment of coronary artery stents by 16 slice computed tomography. Heart. 2006;92:58–61
  55. Schuijf JD, Bax JJ, Jukema JW, Lamb HJ, Warda HM, Vliegen HW, et al. Feasibility of assessment of coronary stent patency using 16-slice computed tomography. Am J Cardiol. 2004;94:427–430
  56. Kitagawa T, Fujii T, Tomohiro Y, Maeda K, Kobayashi M, Kunita E, et al. Noninvasive assessment of coronary stents in patients by 16-slice computed tomography. Int J Cardiol. 2006;109:188–194
  57. Cademartiri F, Mollet N, Lemos PA, Pugliese F, Baks T, McFadden EP, et al. Usefulness of multislice computed tomographic coronary angiography to assess in-stent restenosis. Am J Cardiol. 2005;96:799–802
  58. Gaspar T, Halon DA, Lewis BS, Adawi S, Schliamser JE, Rubinshtein R, et al. Diagnosis of coronary in-stent restenosis with multidetector row spiral computed tomography. J Am Coll Cardiol. 2005;46:1573–1579
  59. Gilard M, Cornily JC, Rioufol G, Finet G, Pennec PY, Mansourati J, et al. Noninvasive assessment of left main coronary stent patency with 16-slice computed tomography. Am J Cardiol. 2005;95:110–112
  60. Van Mieghem CA, Cademartiri F, Mollet NR, Malagutti P, Valgimigli M, Meijboom WB, et al. Multislice spiral computed tomography for the evaluation of stent patency after left main coronary artery stenting: a comparison with conventional coronary angiography and intravascular ultrasound. Circulation. 2006;114:645–653
  61. Rixe J, Achenbach S, Ropers D, Baum U, Kuettner A, Ropers U, et al. Assessment of coronary artery stent restenosis by 64-slice multi-detector computed tomography. Eur Heart J. 2006;27:2567–2572
  62. Oncel D, Oncel G, Karaca M. Coronary stent patency and in-stent restenosis: determination with 64-section multidetector CT coronary angiography--initial experience. Radiology. 2007;242:403–409
  63. Burgstahler C, Beck T, Kuettner A, Drosch T, Kopp AF, Heuschmid M, et al. Non-invasive evaluation of coronary artery bypass grafts using 16-row mutli-slice computed tomography with 188 ms temporal resolution. Int J Cardiol. 2006;106:244–249
  64. Salm LP, Bax JJ, Jukema JW, Schuijf JD, Vliegen HW, Lamb HJ, et al. Comprehensive assessment of patients after coronary artery bypass grafting by 16-detector-row computed tomography. Am Heart J. 2005;150:7757–7781
  65. Anders K, Baum U, Schmid M, Ropers D, Schmid A, Pohle K, et al. Coronary artery bypass graft (CABG) patency: assessment with high-resolution submillimeter 16-slice multidetector-row computed tomography (MDCT) versus coronary angiography. Eur J Radiol. 2006;57:336–344
  66. Ropers D, Pohle FK, Kuettner A, Pflederer T, Anders K, Daniel WG, et al. Diagnostic accuracy of noninvasive coronary angiography in patients after bypass surgery using 64-slice spiral computed tomography with 330-ms gantry rotation. Circulation. 2006;114:2334–2341
  67. Meyer TS, Martinoff S, Hadamitzky M, Will A, Kastrati A, Schomig A, et al. Improved noninvasive assessment of coronary artery bypass grafts with 64-slice computed tomographic angiography in an unselected patient population. J Am Coll Cardiol. 2007;49:946–950
  68. Nieman K, Pattynama PMT, Rensing BJ, van Geins RJM, de Feyter PJ. Evaluation of patients after coronary artery bypass surgery: CT angiographic assessment of grafts and coronary arteries. Radiology. 2003;229:749–756
  69. Martuscelli E, Romagnoli A, D’Eliseo A, Tomassini M, Razzini C, Sperandio M, et al. Evaluation of venous and arterial conduit patency by 16-slice spiral computed tomography. Circulation. 2004;110:3234–3238
  70. Schlosser T, Konorza T, Hunold P, Kuhl H, Schmermund A, Barkhausen J. Noninvasive visualization of coronary artery bypass grafts using 16-detector row computed tomography. J Am Coll Cardiol. 2004;44:1224–1229
  71. Chiurlia E, Menozzi M, Ratti C, Romagnoli R, Modena MG. Follow-up of coronary artery bypass graft patency by multislice computed tomography. Am J Cardiol. 2005;95:1094–1097
  72. Moore RKG, Sampson C, Mac Donald S, Moynahan C, Groves D, Chester MR. Coronary artery bypass graft imaging using ECG-gated multislice computed tomography: Comparison with catheter angiography. Clin Radiol. 2005;60:990–998
  73. Becker CR, Knez A, Ohnesorge B, Schoepf UJ, Reiser MF. Imaging of noncalcified coronary plaques using helical CT with retrospective ECG gating. AJR Am J Roentgenol. 2000;175:423–424
  74. Achenbach S, Moselewski F, Ropers D, Ferencik M, Hoffmann U, MacNeill B, et al. Detection of calcified and noncalcified coronary atherosclerotic plaque by contrast-enhanced, submillimeter multidetector spiral computed tomography: a segment-based comparison with intravascular ultrasound. Circulation. 2004;109:14–17
  75. Leber AW, Knez A, Becker A, Becker C, von Ziegler F, Nikolaou K, et al. Accuracy of multidetector spiral computed tomography in identifying and differentiating the composition of coronary atherosclerotic plaques: a comparative study with intracoronary ultrasound. J Am Coll Cardiol. 2004;43:1241–1247
  76. Schoenhagen P, Tuzcu EM, Stillman AE, Moliterno DJ, Halliburton SS, Kuzmiak SA, et al. Non-invasive assessment of plaque morphology and remodeling in mildly stenostic coronary artery segments: comparison of 16-slice computed tomography and intravascular ultrasound. Coron Artery Dis. 2003;14:459–462
  77. Leber AW, Becker A, Knez A, von Ziegler F, Sirol M, Nikolaou K, et al. Accuracy of 64-slice computed tomography to classify and quantify plaque volumes in the proximal coronary system: a comparative study using intravascular ultrasound. J Am Coll Cardiol. 2006;47:672–677
  78. Achenbach S, Ropers D, Hoffmann U, MacNeill B, Baum U, Pohle K, et al. Assessment of coronary remodeling in stenotic and nonstenotic coronary atherosclerotic lesions by multidetector spiral computed tomography. J Am Coll Cardiol. 2004;43:842–847
  79. Schroeder S, Kopp AF, Baumbach A, Meisner C, Kuettner A, Georg C, et al. Noninvasive detection and evaluation of atherosclerotic coronary plaques with multislice computed tomography. J Am Coll Cardiol. 2001;37:1430–1435
  80. Caussin C, Ohanessian A, Ghostine S, Jacq L, Lancelin B, Dambrin G, et al. Characterization of vulnerable nonstenotic plaque with 16-slice computed tomography compared with intravascular ultrasound. Am J Cardiol. 2004;94:99–100
  81. Becker CR, Nikolaou K, Muders M, Babaryka G, Crispin A, Schoepf UJ, et al. Ex vivo coronary atherosclerotic plaque characterization with multi-detector-row CT. Eur Radiol. 2003;13:2094–2098
  82. Carrascosa PM, Capunay CM, Garcia-Merletti P, Carrascosa J, Garcia MF. Characterization of coronary atherosclerotic plaques by multidetector computed tomography. Am J Cardiol. 2006;97:598–602
  83. Pohle K, Achenbach S, MacNeill B, Ropers D, Ferencik M, Moselewski F, et al. Characterization of non-calcified coronary atherosclerotic plaque by multi-detector row CT: comparison to IVUS. Atherosclerosis. 2007;190:174–180
  84. Moselewski F, Ropers D, Pohle K, Hoffmann U, Ferencik M, Chan RC, et al. Comparison of measurement of cross-sectional coronary atherosclerotic plaque and vessel areas by 16-slice multidetector computed tomography versus intravascular ultrasound. Am J Cardiol. 2004;94:1294–1297
  85. Leber AW, Knez A, White CW, Becker A, von Ziegler F, Muehling O, et al. Composition of coronary atherosclerotic plaques in patients with acute myocardial infarction and stable angina pectoris determined by contrast-enhanced multislice computed tomography. Am J Cardiol. 2003;91:714–718
  86. Inoue F, Sato Y, Matsumoto N, Tani S, Uchiyama T. Evaluation of plaque texture by means of multislice computed tomography in patients with acute coronary syndrome and stable angina. Circ J. 2004;68:840–844
  87. Hoffmann U, Moselewski F, Nieman K, Jang IK, Ferencik M, Rahman AM, et al. Noninvasive assessment of plaque morphology and composition in culprit and stable lesions in acute coronary syndrome and stable lesions in stable angina by multidetector computed tomography. J Am Coll Cardiol. 2006;47:1655–1662
  88. Pundzuite G, Schuijf JD, Jukema JW, Boersma E, de Roos A, van der Wall EE, et al. Prognostic value of multislice computed tomography coronary angiography in patients with known or suspected coronary artery disease. J Am Coll Cardiol. 2007;49:62–70

 Conflict of interest: Dr Achenbach reports receiving research grants from Siemens, Pfizer, and Schering and being a consultant to Bracco and Bristol-Myers Squibb

PII: S1934-5925(07)00008-1

doi: 10.1016/j.jcct.2007.04.007

Journal of Cardiovascular Computed Tomography
Volume 1, Issue 1 , Pages 3-20 , July 2007

Article Tools

* Image Usage & Resolution