Journal of Cardiovascular Computed Tomography
Volume 2, Issue 1 , Pages 26-32 , January 2008

Automated multidetector computed tomography evaluation of subacutely infarcted myocardium

  • Balázs Ruzsics, MD

      Affiliations

    • Department of Biochemistry and Molecular Genetics, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    • ,
  • Pál Surányi, MD

      Affiliations

    • Department of Biochemistry and Molecular Genetics, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    • ,
  • Pál Kiss, MD

      Affiliations

    • Department of Biochemistry and Molecular Genetics, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    • ,
  • Brigitta C. Brott, MD

      Affiliations

    • Department of Medicine (Cardiovascular Disease), University of Alabama at Birmingham, Birmingham, AL 35294, USA
    • ,
  • Satinder S. Singh, MD

      Affiliations

    • Department of Radiology, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    • ,
  • Silvio Litovsky, MD

      Affiliations

    • Department of Anatomic Pathology, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    • ,
  • Inmaculada Aban, PhD

      Affiliations

    • Department of Biostatistics, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    • ,
  • Steven G. Lloyd, MD, PhD

      Affiliations

    • Department of Medicine (Cardiovascular Disease), University of Alabama at Birmingham, Birmingham, AL 35294, USA
    • ,
  • Tamas Simor, MD, PhD

      Affiliations

    • Department of Biochemistry and Molecular Genetics, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    • ,
  • Gabriel A. Elgavish, PhD

      Affiliations

    • Department of Medicine (Cardiovascular Disease), University of Alabama at Birmingham, Birmingham, AL 35294, USA
    • Department of Biochemistry and Molecular Genetics, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    • ,
  • Himanshu Gupta, MD

      Affiliations

    • Department of Medicine (Cardiovascular Disease), University of Alabama at Birmingham, Birmingham, AL 35294, USA
    • Corresponding Author InformationCorresponding author.

Received 30 May 2007 ,Accepted 7 November 2007.

References 

  1. Choi CJ, Haji-Momenian S, Dimaria JM, Epstein FH, Bove CM, Rogers WJ, et al. Infarct involution and improved function during healing of acute myocardial infarction: the role of microvascular obstruction. J Cardiovasc Magn Reson. 2004;6(4):917–925
  2. Gerber BL, Rochitte CE, Melin JA, McVeigh ER, Blueme DA, Wu KC, et al. Microvascular obstruction and left ventricular remodeling early after acute myocardial infarction. Circulation. 2000;101:2734–2741
  3. Judd RM, Lugo-Olivieri CH, Arai M, Kondo T, Croisille P, Lima JA, et al. Physiological basis of myocardial contrast enhancement in fast magnetic resonance images of 2-day-old reperfused canine infarcts. Circulation. 1995;92:1902–1910
  4. Fieno DS, Kim RJ, Chen EL, Lomasney JW, Klocke FJ, Judd RM. Contrast-enhanced magnetic resonance imaging of myocardium at risk: distinction between reversible and irreversible injury throughout infarct healing. J Am Coll Cardiol. 2000;36:1985–1991
  5. Lund GK, Stork A, Saeed M, Bansmann MP, Gerken JH, Muller V, et al. Acute myocardial infarction: evaluation with first-pass enhancement and delayed enhancement MR imaging compared with 201Tl SPECT imaging. Radiology. 2004;232:49–57
  6. Lardo AC, Cordeiro MA, Silva C, Amado LC, George RT, Saliaris AP, et al. Contrast-enhanced multidetector computed tomography viability imaging after myocardial infarction: characterization of myocyte death, microvascular obstruction, and chronic scar. Circulation. 2006;113:394–404
  7. Gerber BL, Belge B, Legros GJ, Lim P, Poncelet A, Pasquet A, et al. Characterization of acute and chronic myocardial infarcts by multidetector computed tomography: comparison with contrast-enhanced magnetic resonance. Circulation. 2006;113(6):823–833
  8. Turschner O, D’hooge J, Dommke C, Claus P, Verbeken E, De Scheerder I, et al. The sequential changes in myocardial thickness and thickening which occur during acute transmural infarction, infarct reperfusion and the resultant expression of reperfusion injury. Eur Heart J. 2004;25:794–803
  9. Bland JM, Altman DG. Statistical methods for assessing agreement between two methods of clinical measurement. Lancet. 1986;1(8476):307–310
  10. Baks T, Cademartiri F, Moelker AD, Weustink AC, van Geuns RJ, Mollet NR, et al. Multislice computed tomography and magnetic resonance imaging for the assessment of reperfused acute myocardial infarction. J Am Coll Cardiol. 2006;48:144–152
  11. Wu KC, Kim RJ, Bluemke DA, Rochitte CE, Zerhouni EA, Becker LC, et al. Quantification and time course of microvascular obstruction by contrast-enhanced echocardiography and magnetic resonance imaging following acute myocardial infarction and reperfusion. J Am Coll Cardiol. 1998;32:1756–1764

 Conflict of interest: Dr. Surányi and Dr. Kiss were employees of Elgavish Paramagnetics Inc., Birmingham, AL. Dr. Elgavish is the president of Elgavish Paramagnetics Inc. The other authors report no conflicts of interest.

 Mailing address: BDB 101, CVMRI, University of Alabama at Birmingham, 1808 7th Ave. South, Birmingham, AL 35294.

PII: S1934-5925(07)00345-0

doi: 10.1016/j.jcct.2007.11.003

Journal of Cardiovascular Computed Tomography
Volume 2, Issue 1 , Pages 26-32 , January 2008

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