Journal of Cardiovascular Computed Tomography
Volume 2, Issue 2 , Pages 105-114 , March 2008

Image quality and artifacts in coronary CT angiography with dual-source CT: Initial clinical experience

  • Damini Dey, PhD

      Affiliations

    • Department of Imaging, Cedars-Sinai Medical Center, 8700 Beverly Boulevard, Taper Building, A1258, Los Angeles, CA 90048, USA
    • David-Geffen School of Medicine, University of California-Los Angeles, Los Angeles, CA, USA
  • ,
  • Cynthia J. Lee, DO

      Affiliations

    • Capitol Hearts Associates, P.C., Washington, D.C., USA
  • ,
  • Muneo Ohba, MD

      Affiliations

    • Department of Imaging, Cedars-Sinai Medical Center, 8700 Beverly Boulevard, Taper Building, A1258, Los Angeles, CA 90048, USA
  • ,
  • Ariel Gutstein, MD

      Affiliations

    • Department of Imaging, Cedars-Sinai Medical Center, 8700 Beverly Boulevard, Taper Building, A1258, Los Angeles, CA 90048, USA
  • ,
  • Piotr J. Slomka, PhD, FCCPM

      Affiliations

    • Department of Imaging, Cedars-Sinai Medical Center, 8700 Beverly Boulevard, Taper Building, A1258, Los Angeles, CA 90048, USA
    • David-Geffen School of Medicine, University of California-Los Angeles, Los Angeles, CA, USA
  • ,
  • Victor Cheng, MD

      Affiliations

    • Department of Imaging, Cedars-Sinai Medical Center, 8700 Beverly Boulevard, Taper Building, A1258, Los Angeles, CA 90048, USA
  • ,
  • Yasuyuki Suzuki, MD

      Affiliations

    • Department of Imaging, Cedars-Sinai Medical Center, 8700 Beverly Boulevard, Taper Building, A1258, Los Angeles, CA 90048, USA
  • ,
  • Shoji Suzuki, MD

      Affiliations

    • Department of Imaging, Cedars-Sinai Medical Center, 8700 Beverly Boulevard, Taper Building, A1258, Los Angeles, CA 90048, USA
  • ,
  • Arik Wolak, MD

      Affiliations

    • Department of Imaging, Cedars-Sinai Medical Center, 8700 Beverly Boulevard, Taper Building, A1258, Los Angeles, CA 90048, USA
  • ,
  • Ludovic Le Meunier, PhD

      Affiliations

    • Siemens Medical Solutions (PET Division), Knoxville, TN, USA
  • ,
  • Louise E.J. Thomson, MD, MBChB FRACP

      Affiliations

    • Department of Imaging, Cedars-Sinai Medical Center, 8700 Beverly Boulevard, Taper Building, A1258, Los Angeles, CA 90048, USA
    • David-Geffen School of Medicine, University of California-Los Angeles, Los Angeles, CA, USA
  • ,
  • Ishac Cohen, PhD

      Affiliations

    • Department of Imaging, Cedars-Sinai Medical Center, 8700 Beverly Boulevard, Taper Building, A1258, Los Angeles, CA 90048, USA
  • ,
  • John D. Friedman, MD, FACC

      Affiliations

    • Department of Imaging, Cedars-Sinai Medical Center, 8700 Beverly Boulevard, Taper Building, A1258, Los Angeles, CA 90048, USA
    • David-Geffen School of Medicine, University of California-Los Angeles, Los Angeles, CA, USA
  • ,
  • Guido Germano, PhD, FACC

      Affiliations

    • Department of Imaging, Cedars-Sinai Medical Center, 8700 Beverly Boulevard, Taper Building, A1258, Los Angeles, CA 90048, USA
    • David-Geffen School of Medicine, University of California-Los Angeles, Los Angeles, CA, USA
  • ,
  • Daniel S. Berman, MD, FACC

      Affiliations

    • Department of Imaging, Cedars-Sinai Medical Center, 8700 Beverly Boulevard, Taper Building, A1258, Los Angeles, CA 90048, USA
    • David-Geffen School of Medicine, University of California-Los Angeles, Los Angeles, CA, USA
    • Corresponding Author InformationCorresponding author.

Received 25 August 2007 ,Accepted 21 December 2007.

References 

  1. Achenbach S, Ropers D, Kuettner A, Flohr T, Ohnesorge B, Bruder H, et al. Contrast-enhanced coronary artery visualization by dual-source computed tomography–initial experience. Eur J Radiol. 2006;57:331–335
  2. Flohr TG, McCollough CH, Bruder H, Petersilka M, Gruber K, Suss C, et al. First performance evaluation of a dual-source CT (DSCT) system. Eur Radiol. 2006;16:256–268
  3. Achenbach S. Computed tomography coronary angiography. J Am Coll Cardiol. 2006;48:1919–1928
  4. Morin RL, Gerber TC, McCollough CH. Radiation dose in computed tomography of the heart. Circulation. 2003;107:917–922
  5. Agatston AS, Janowitz WR, Hildner JF, Zusmer NR, Viamonte M, Detrano R. Quantification of coronary artery calcium using ultrafast computed tomography. J Am Coll Cardiol. 1990;15:827–832
  6. Matt D, Scheffel H, Leschka S, Flohr TG, Marincek B, Kaufmann PA, et al. Dual-source CT coronary angiography: image quality, mean HR, and HR variability. AJR Am J Roentgenol. 2007;189:567–573
  7. Dey D, Slomka P, Chien D, Fieno D, Abidov A, Saouaf R, et al. Direct quantitative in vivo comparison of calcified atherosclerotic plaque on vascular MRI and CT by multimodality image registration. J Magn Reson Imaging. 2006;23:345–354
  8. Ohnesorge BM, Flohr TG, Becker CR, Knez A, Reiser MF. Multi-slice and Dual-source CT in Cardiac Imaging. Berlin, Germany: Springer-Verlag; 2007;
  9. Hoffmann U, Ferencik M, Cury RC, Pena AJ. Coronary CT angiography. J Nucl Med. 2006;47:797–806
  10. Austen WG, Edwards JE, Frye RL, Gensini GG, Gott VL, Griffith LS, et al. A reporting system on patients evaluated for coronary artery disease (Report of the Ad Hoc Committee for Grading of Coronary Artery Disease, Council on Cardiovascular Surgery, American Heart Association). Circulation. 1975;51:5–40
  11. Leber AW, Knez A, von Ziegler F, Becker A, Nikolaou K, Paul S, et al. Quantification of obstructive and nonobstructive coronary lesions by 64-slice computed tomography: a comparative study with quantitative coronary angiography and intravascular ultrasound. G. J Am Coll Cardiol. 2005;46:147–154
  12. Leschka S, Alkadhi H, Plass A, Desbiolles L, Grunenfelder J, Marincek B, et al. Accuracy of MSCT coronary angiography with 64-slice technology: first experience. Eur Heart J. 2005;26:1482–1487
  13. Raff GL, Gallagher MJ, O’Neill WW, Goldstein JA. Diagnostic accuracy of noninvasive coronary angiography using 64-slice spiral computed tomography. J Am Coll Cardiol. 2005;46:552–557
  14. Mollet NR, Cademartiri F, van Mieghem CA, Runza G, McFadden EP, Baks T, et al. High-resolution spiral computed tomography coronary angiography in patients referred for diagnostic conventional coronary angiography. Circulation. 2005;112:2318–2323
  15. Leschka S, Wildermuth S, Boehm T, Desbiolles L, Husmann L, Plass A, et al. Noninvasive coronary angiography with 64-section CT: effect of average HR and HR variability on image quality. Radiology. 2006;241:378–385
  16. Berman DS, Hachamovitch R, Shaw LJ, Friedman JD, Hayes SW, Thomson LE, et al. Roles of nuclear cardiology, cardiac computed tomography, and cardiac magnetic resonance: assessment of patients with suspected coronary artery disease. J Nucl Med. 2006;47:74–82
  17. Slomka PJ, Berman DS, Germano G. Applications and software techniques for integrated cardiac multimodality imaging. Expert Rev Cardiovasc Ther. 2008;6:27–41
  18. Gaemperli O, Schepis T, Valenta I, Husmann L, Scheffel H, Duerst V, et al. Cardiac image fusion from stand-alone SPECT and CT: clinical experience. J Nucl Med. 2007;48:696–703
  19. Joseph P, Spital R. The exponential edge-gradient effect in x-ray computed tomography. Phys Med Biol. 1981;26:473–487
  20. Flohr T, Schoepf U, Kuettner A, Halliburton S, Bruder H, Suess C, et al. Advances in cardiac imaging with 16-section CT systems. Acad Radiol. 2003;10:386–401
  21. Prokop M, Galanski M, van der Molen AJ, Schaefer-Prokop CM. Spiral and Multislice Computed Tomography of the Body. New York, NY: Thieme; 2003;
  22. Johnson TR, Nikolaou K, Wintersperger BJ, Leber AW, von Ziegler F, Rist C, et al. Dual-source CT cardiac imaging: initial experience. Eur Radiol. 2006;13:13
  23. Wintersperger BJ, Nikolaou K, von Ziegler F, Johnson T, Rist C, Leber A, et al. Image quality, motion artifacts, and reconstruction timing of 64-slice coronary computed tomography angiography with 0.33-second rotation speed. Invest Radiol. 2006;41:436–442
  24. McCollough CH, Primak AN, Saba O, Bruder H, Stierstorfer K, Raupach R, et al. Dose performance of a 64-channel dual-source CT scanner. Radiology. 2007;243:775–784
  25. Gutstein A, Dey D, Cheng V, Wolak A, Suzuki Y, Friedman J, et al. A novel approach to optimized radiation dose reduction during multiphase coronary CTA with dual source CT. 2008;Accepted for presentation at the annual meeting of the American College of Cardiology

 Conflict of interest: Dr. Le Meunier is an employee of Siemens Medical Systems, PET Division. The other authors report no conflicts of interest.This study was supported by in part by grant 6318 from the Glazer Foundation, Los Angeles, CA, and in part by The Lincy Foundation, Los Angeles, CA.

PII: S1934-5925(08)00046-4

doi: 10.1016/j.jcct.2007.12.017

Journal of Cardiovascular Computed Tomography
Volume 2, Issue 2 , Pages 105-114 , March 2008