Journal of Cardiovascular Computed Tomography
Volume 3, Issue 1 , Pages 35-42 , January 2009

Improved noninvasive coronary angiography in morbidly obese patients with dual-source computed tomography

  • Kavitha M. Chinnaiyan, MD, FACC

      Affiliations

    • Division of Cardiology, William Beaumont Hospital,3601 W 13 Mile Road, Royal Oak, MI 48073,USA
    • Corresponding Author InformationCorresponding author.
    • ,
  • Peter A. McCullough, MD, MPH, FACC, FACP, FAHA, FCCP

      Affiliations

    • Nutrition and Preventive Medicine, William Beaumont Hospital,3601 W 13 Mile Road, Royal Oak, MI 48073,USA
    • ,
  • Thomas G. Flohr, PhD

      Affiliations

    • Siemens HealthCare, Computed Tomography, Siemensstr #1, 91301, Forchheim, Germany
    • ,
  • James H. Wegner, BS

      Affiliations

    • Division of Cardiology, William Beaumont Hospital,3601 W 13 Mile Road, Royal Oak, MI 48073,USA
    • ,
  • Gilbert L. Raff, MD, FACC

      Affiliations

    • Division of Cardiology, William Beaumont Hospital,3601 W 13 Mile Road, Royal Oak, MI 48073,USA

Received 24 July 2008 ,Accepted 25 November 2008.

References 

  1. A Nation at Risk: Obesity in the United States Statistical Sourcebook. Dallas, TX: American Heart Association, 2005. Available at: www.americanheart.org/presenter.jhtml?identifier=3030570. Accessed June 30, 2008.
  2. Flegal KM, Carroll MD, Kuczmarski RJ, Johnson CL. Overweight and obesity in the United States: prevalence and trends, 1960–1994. Int J Obes Relat Metab Disord. 1998;22:39–47
  3. Brown CD, Higgins M, Donato KA, Rohde FC, Garrison R, Obarzanek E, et al. Body mass index and the prevalence of hypertension and dyslipidemia. Obes Res. 2000;8:605–619
  4. Wilson PW, D'Agostino RB, Sullivan L, Parise H, Kannel WB. Overweight and obesity as determinants of cardiovascular risk: the Framingham experience. Arch Intern Med. 2002;162:1867–1872
  5. Flegal KM, Graubard BI, Williamson DF, Gail MH. Excess deaths associated with underweight, overweight, and obesity. JAMA. 2005;293:1861–1867
  6. Burke GL, Bertoni AG, Shea S, Tracy R, Watson KE, Blumenthal RS, et al. The impact of obesity on cardiovascular disease risk factors and subclinical vascular disease. Arch Intern Med. 2008;168(9):928–935
  7. Romero-Corall A, Montori VM, Somers VK, Korinek J, Thomas RJ, Allison TG, et al. Lopez-JimenezF: Association of bodyweight with total mortality and with cardiovascular events in coronary artery disease: a systematic review of cohort studies. Lancet. 2006;368(9536):666–678
  8. Raff GL, Goldstein JA. Coronary angiography by computed tomography. coronary imaging evolves. J Am Coll Cardiol. 2007;49:1830–1833
  9. Yoshimura N, Sabir A, Kubo T, Lin PJ, Clouse ME, Hatabu H. Correlation between image noise and body weight in coronary CTA with 16-row MDCT. Acad Radiol. 2006;13:324–328
  10. Raff GL, Gallagher MJ, O'Neill WW, Goldstein JA. Diagnostic accuracy of noninvasive coronary angiography using 64-slice spiral computed tomography. J Am Coll Cardiol. 2005;46:552–557
  11. Flohr TG, McCullough CH, Bruder H, Petersilka M, Gruber K, Suss C, et al. First performance evaluation of a dual-source CT (DSCT) system. Eur Radiol. 2006;16:256–268
  12. Scheffel H, Alkadhi H, Plass A, Vachenauer R, Desbiolles L, Gaemperli O, et al. Accuracy of dual-source CT coronary angiography: first experience in a high pre-test probability population without heart rate control. Eur Radiol. 2006;16(12):2739–2747
  13. Ropers U, Ropers D, Pflederer T, Anders K, Kuettner A, Stilianakis NI, et al. Influence of heart rate on the diagnostic accuracy of dual-source computed tomography coronary angiography. J Am Coll Cardiol. 2007;50(25):2393–2398
  14. Matt D, Scheffel H, Leschka S, Flohr TG, Marincek B, Kaufmann PA, et al. Dual-source CT coronary angiography: image quality, mean heart rate, and heart rate variability. AJR Am J Roentgenol. 2007;189(3):567–573
  15. Johnson TR, Nikolaou K, Busch S, Leber AW, Becker A, Wintersperger BJ, et al. Diagnostic accuracy of dual-source computed tomography in the diagnosis of coronary artery disease. Invest Radiol. 2007;42(10):684–691
  16. Leber AW, Johnson T, Becker A, von Ziegler F, Tittus J, Nikolaou K, et al. Diagnostic accuracy of dual-source multi-slice CT-coronary angiography in patients with an intermediate pretest likelihood for coronary artery disease. Eur Heart J. 2007;28(19):2354–2360
  17. Schmidt B, Kalender WA. A fast-voxel-based Monte Carlo method for scanner and patient-specific dose calculations in computed tomography. In:  Guerra AD editors. Physica Medica. Erlangen, Germany: European Journal of Medical Physics; 2002;p. 43–53
  18. Austen WG, Edwards JE, Frye RL, Gensini GG, Gott VL, Griffith LS, et al. A reporting system on patients evaluated for coronary artery disease. Report of the ad-hoc committee for Grading of Coronary Artery Disease, Council on Cardiovascular Surgery. Circulation. 1975;51:5–40
  19. McCollough CH, Primak AN, Saba OB, Bruder H, Stierstorfer K, Raupach R, et al. Dose performance of a 64-channel dual-source CT scanner. Radiology. 2007;243(3):775–784
  20. Duvall WL, Corft LB, Corriel JS, Einstein AJ, Fisher JE, Haynes PS, et al. SPECT myocardial perfusion imaging in morbidly obese patients: image quality, hemodynamic response to pharmacologic stress, and diagnostic and prognostic value. J Nucl Cardiol. 2006;13:202–209
  21. Madu EC. Transesophageal dobutamine stress echocardiography in the evaluation of myocardial ischemia in morbidly obese subjects. Chest. 2000;117:657–661
  22. McNulty PH, Ettinger SM, Field JM, Gilchrist IC, Kozak M, Chambers CE, et al. Cardiac catheterization in morbidly obese patients. Cathet Cardiovasc Intervent. 2002;56:174–177
  23. Cox N, Resnic FS, Popma JJ, Simon DI, Eisenhauer AC, Rogers C. Comparison of the risk of vascular complications associated with femoral and radial access coronary catheterization procedures in obese versus nonobese patients. Am J Cardiol. 2004;94:1174–1177
  24. Hausleiter J, Hermann F, Meyer T, et al. A new algorithm for ECG-based tube current modulation (“MinDose”) reduces radiation dose estimates in cardiac dual source CT angiography (abstract). Circulation. 2007;116:II-575

 Conflict of interest: Dr. Flohr is an employee of Siemens HealthCare. The other authors report no conflicts of interest.

 This research was supported by grants from Bayer HealthCare Pharmaceuticals (K.M.C.), Siemens HealthCare (G.L.R.), and the Florine and J. Peter Ministrelli Advanced Cardiovascular Imaging Center.

PII: S1934-5925(08)00708-9

doi: 10.1016/j.jcct.2008.11.003

Journal of Cardiovascular Computed Tomography
Volume 3, Issue 1 , Pages 35-42 , January 2009

Article Tools

* Image Usage & Resolution