Journal of Cardiovascular Computed Tomography
Volume 4, Issue 4 , Pages 267-273 , July 2010

Cardiac computed tomography for prediction of myocardial viability after reperfused acute myocardial infarction

  • Michael D. Shapiro, DO

      Affiliations

    • Cardiac MR PET CT Program, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA
    • Division of Cardiovascular Medicine, Oregon Health and Science University, Portland, OR, USA
  • ,
  • Ammar Sarwar, MD

      Affiliations

    • Cardiac MR PET CT Program, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA
    • Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA
  • ,
  • Koen Nieman, MD

      Affiliations

    • Cardiac MR PET CT Program, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA
  • ,
  • Khurram Nasir, MD, MPH

      Affiliations

    • Cardiac MR PET CT Program, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA
  • ,
  • Thomas J. Brady, MD

      Affiliations

    • Cardiac MR PET CT Program, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA
  • ,
  • Ricardo C. Cury, MD

      Affiliations

    • Cardiac MR PET CT Program, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA
    • Cardiovascular MR and CT Program, Baptist Cardiac and Vascular Institute, 8900 N Kendall Drive, Miami, FL 33176, USA
    • Corresponding Author InformationCorresponding author.

Received 6 December 2009 ,Accepted 6 April 2010.

References 

  1. Jacobs AK, Antman EM, Ellrodt G, Faxon DP, Gregory T, Mensah GA, et al. American Heart Association's Acute Myocardial Infarction Advisory Working Group: Recommendation to develop strategies to increase the number of ST-segment-elevation myocardial infarction patients with timely access to primary percutaneous coronary intervention. Circulation. 2006;113:2152–2163
  2. Judd RM, Lugo-Olivieri CH, Arai M, Kondo T, Croisille P, Lima JA, et al. Physiological basis of myocardial contrast enhancement in fast magnetic resonance images of 2-day-old reperfused canine infarcts. Circulation. 1995;92:1902–1910
  3. Kim RJ, Fieno DS, Parrish TB, Harris K, Chen EL, Simonetti O, et al. Relationship of MRI delayed contrast enhancement to irreversible injury, infarct age, and contractile function. Circulation. 1999;100:1992–2002
  4. Kim RJ, Wu E, Rafael A, Chen EL, Parker MA, Simonetti O, et al. The use of contrast-enhanced magnetic resonance imaging to identify reversible myocardial dysfunction. N Engl J Med. 2000;343:1445–1453
  5. Gerber BL, Garot J, Bluemke DA, Wu KC, Lima JA. Accuracy of contrast-enhanced magnetic resonance imaging in predicting improvement of regional myocardial function in patients after acute myocardial infarction. Circulation. 2002;106:1083–1119
  6. Beek AM, Kuhl HP, Bondarenko O, Twisk JW, Hofman MB, van Dockum WG, et al. Delayed contrast-enhanced magnetic resonance imaging for the prediction of regional functional improvement after acute myocardial infarction. J Am Coll Cardiol. 2003;42:895–901
  7. Choi KM, Kim RJ, Gubernikoff G, Vargas JD, Parker M, Judd RM. Transmural extent of acute myocardial infarction predicts long-term improvement in contractile function. Circulation. 2001;104:1101–1107
  8. Shapiro MD, Nieman K, Nasir K, Nomura CH, Sarwar A, Ferencik M, et al. Utility of cardiovascular magnetic resonance to predict left ventricular recovery after primary percutaneous coronary intervention for patients presenting with acute ST-segment elevation myocardial infarction. Am J Cardiol. 2007;100:211–216
  9. Mahnken AH, Bruners P, Katoh M, Wildberger JE, Gunther RW, Buecker A. Dynamic multi-section CT imaging in acute myocardial infarction: preliminary animal experience. Eur Radiol. 2006;16:746–752
  10. Lardo AC, Cordeiro MA, Silva C, Amado LC, George RT, Saliaris AP, et al. Contrast-enhanced multidetector computed tomography viability imaging after myocardial infarction: characterization of myocyte death, microvascular obstruction, and chronic scar. Circulation. 2006;113:394–404
  11. Mahnken AH, Koos R, Katoh M, Wildberger JE, Spuentrup E, Buecker A, et al. Assessment of myocardial viability in reperfused acute myocardial infarction using 16-slice computed tomography in comparison to magnetic resonance imaging. J Am Coll Cardiol. 2005;45:2042–2047
  12. Gerber BL, Belge B, Legros GJ, Lim P, Poncelet A, Pasquet A, et al. Characterization of acute and chronic myocardial infarcts by multidetector computed tomography: comparison with contrast-enhanced magnetic resonance. Circulation. 2006;113:823–833
  13. Habis M, Capderou A, Ghostine S, Daoud B, Caussin C, Riou JY, et al. Acute myocardial infarction early viability assessment by 64-slice computed tomography immediately after coronary angiography: comparison with low-dose dobutamine echocardiography. J Am Coll Cardiol. 2007;49:1178–1185
  14. Flohr T, Stierstorfer K, Raupach R, Ulzheimer S, Bruder H. Performance evaluation of a 64-slice CT system with z-flying focal spot. Rofo. 2004;176:1803–1810
  15. Cerqueira MD, Weissman NJ, Dilsizian V, Jacobs AK, Kaul S, Laskey WK, et al. American Heart Association Writing Group on Myocardial Segmentation and Registration for Cardiac Imaging: Standardized myocardial segmentation and nomenclature for tomographic imaging of the heart: a statement for healthcare professionals from the Cardiac Imaging Committee of the Council on Clinical Cardiology of the American Heart Association. Circulation. 2002;105:539–542
  16. Nieman K, Shapiro MD, Ferencik M, Nomura CH, Abbara S, Hoffmann U, et al. Reperfused myocardial infarction: contrast-enhanced 64-Section CT in comparison to MR imaging. Radiology. 2008;247:49–56
  17. Flohr TG, Stierstorfer K, Ulzheimer S, Bruder H, Primak AN, McCollough CH. Image reconstruction and image quality evaluation for a 64-slice CT scanner with z-flying focal spot. Med Phys. 2005;32:2536–2547
  18. Koyama Y, Matsuoka H, Mochizuki T, Higashino H, Kawakami H, Nakata S, et al. Assessment of reperfused acute myocardial infarction with two-phase contrast-enhanced helical CT: prediction of left ventricular function and wall thickness. Radiology. 2005;235:804–811
  19. Wada H, Kobayashi Y, Yasu T, Tsukamoto Y, Kobayashi N, Ishida T, et al. Multi-detector computed tomography for imaging of subendocardial infarction: prediction of wall motion recovery after reperfused anterior myocardial infarction. Circ J. 2004;68:512–514
  20. Lessick J, Dragu R, Mutlak D, Rispler S, Beyar R, Litmanovich D, et al. Is functional improvement after myocardial infarction predicted with myocardial enhancement patterns at multidetector CT?. Radiology. 2007;244:736–744
  21. Kachenoura N, Gaspar T, Lodato JA, Bardo DM, Newby B, Gips S, et al. Combined assessment of coronary anatomy and myocardial perfusion using multidetector computed tomography for the evaluation of coronary artery disease. Am J Cardiol. 2009;103:1487–1494
  22. Kachenoura N, Lodato JA, Gaspar T, Bardo DM, Newby B, Gips S, et al. Value of multidetector computed tomography evaluation of myocardial perfusion in the assessment of ischemic heart disease: comparison with nuclear perfusion imaging. Eur Radiol. 2009;19:1897–1905

 Conflict of interest: The authors report no conflicts of interest.

 Dr. Shapiro and Dr. Nasir have received support from NIH grant 1T32 HL076136-02.

PII: S1934-5925(10)00256-X

doi: 10.1016/j.jcct.2010.04.004

Journal of Cardiovascular Computed Tomography
Volume 4, Issue 4 , Pages 267-273 , July 2010