Introduction: Cardiac resynchronization therapy (CRT) is a proven treatment for heart failure patients.
However, 1/3rd of these patients do not respond positively to the treatment due to suboptimal lead
placement. Non-reproducible results with echocardiography and the limited availability
of cardiac MR especially for patients with existing RV leads (28%) coupled with its
requirement for highly skilled operators necessitates the requirement for a robust
imaging modality for guiding therapy. By developing an LV phantom with programmable
dyssynchrony, we intend to evaluate the efficacy of 4DCT with SQUEEZ processing in
guiding CRT. As initial validation, we compare the programmed regional shortening
(RSct) values with those obtained by 3D printing and imaging different phases of the
LV phantom using a CT scanner.
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© 2020 Published by Elsevier Inc.
