Abstract| Volume 14, ISSUE 3, SUPPLEMENT , S69, July 2020

Anthropomorphic Dyssynchronous LV Phantom: A Framework To Investigate The Assessment Of LV Dyssynchrony Using 4DCT-SQUEEZ

      Introduction: Cardiac resynchronization therapy (CRT) is a proven treatment for heart failure patients. However, 1/3rd of these patients do not respond positively to the treatment due to suboptimal lead placement. Non-reproducible results with echocardiography and the limited availability of cardiac MR especially for patients with existing RV leads (28%) coupled with its requirement for highly skilled operators necessitates the requirement for a robust imaging modality for guiding therapy. By developing an LV phantom with programmable dyssynchrony, we intend to evaluate the efficacy of 4DCT with SQUEEZ processing in guiding CRT. As initial validation, we compare the programmed regional shortening (RSct) values with those obtained by 3D printing and imaging different phases of the LV phantom using a CT scanner.
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