Abstract
Background
Aim of the present study was to verify the feasibility and accuracy of live integration
of myocardial fibrosis evaluated at CCT with EAM (electro-anatomical mapping).
Methods
We prospectively enrolled a consecutive cohort of patients with clinical indication
to EAM before radiofrequency catheter ablation (RFCA) of refractory ventricular tachycardia
(VT) and an absolute contraindication to cardiac magnetic resonance. All patients
underwent per protocol CCT for myocardial fibrosis and coronary anatomy evaluation.
Diagnostic performance was assessed for myocardial fibrosis evaluation with CCT vs
EAM. Live integration feasibility of CCT vs EAM was evaluated for every patients.
Results
A total of 19 patients were included in the present study with 323 myocardial segments
analyzed for myocardial fibrosis at CCT. In all patients CCT data were successfully
integrated with EAM during RFCA procedure. All patients had myocardial fibrosis correctly
identified at CCT vs EAM on a per-patients basis. A diagnostic accuracy on a per-segment
basis of 94.1% for detection of any type of myocardial fibrosis at CCT vs EAM was
recorded.
Conclusions
CCT identification of myocardial fibrosis is feasible and accurate vs EAM in a very
selected high risk patients with clinical indication to RFCA of VT and contraindication
to CMR.
Graphical abstract

Graphical Abstract
Keywords
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Article info
Publication history
Published online: December 21, 2021
Accepted:
December 13,
2021
Received:
October 27,
2021
Identification
Copyright
© 2021 Society of Cardiovascular Computed Tomography. Published by Elsevier Inc. All rights reserved.