Live integration of comprehensive cardiac CT with electroanatomical mapping in patients with refractory ventricular tachycardiaAim of the present study was to verify the feasibility and accuracy of live integration of myocardial fibrosis evaluated at CCT with EAM (electro-anatomical mapping).
Comparison of coronary atherosclerotic plaque progression in East Asians and Caucasians by serial coronary computed tomographic angiography: A PARADIGM substudyTo investigate potential differences in plaque progression (PP) between in East Asians and Caucasians as well as to determine clinical predictors of PP in East Asians.
Percent atheroma volume: Optimal variable to report whole-heart atherosclerotic plaque burden with coronary CTA, the PARADIGM studyDifferent methodologies to report whole-heart atherosclerotic plaque on coronary computed tomography angiography (CCTA) have been utilized. We examined which of the three commonly used plaque burden definitions was least affected by differences in body surface area (BSA) and sex.
State-of-the-art-myocardial perfusion stress testing: Static CT perfusionLarge multicenter studies and meta-analysis have documented the diagnostic accuracy and the prognostic implications of stress echocardiography, cardiac magnetic resonance and, mainly, nuclear stress tests. However, none of them provides a comprehensive anatomical and functional evaluation within the same study as stress CT perfusion. Myocardial CT perfusion is the only non-invasive modality that allows to quantifying coronary stenosis and determining its functional relevance, constituting a potential “one-stop-shop” method for the diagnosis and global management of patients with known or suspected coronary artery disease.
Cardiovascular morbidity and mortality in patients with aortic valve calcification: A systematic review and meta-analysisAortic valve calcification (AVC) is an active process that involves inflammation, disorganization of matrix disposition, lipid accumulation and lamellar bone formation. AVC without hemodynamic changes has been associated with cardiovascular (CV) risk factors and increased risk of coronary and CV events. Nowadays, echocardiography is the standard imaging technique to evaluate aortic valve pathologies. However, cardiac computed tomography (CT) allows high accuracy and reproducible measurement of AVC, without exposing the patients to excessive radiation or contrast administration.
Left-dominant arrhythmogenic cardiomyopathy diagnosed at cardiac CTA 71 years-old man was referred to our Center after detection of a non-sustained ventricular tachycardia (NSVT) at ambulatory electrocardiogram (ECG) monitoring. His previous cardiological history was negative. Rest ECG showed negative T-waves on V4 V6 leads (Panel A). Blood examination was normal including high-sensitive troponin-I and C-reactive protein. Transthoracic echocardiography showed normal biventricular wall kinesis and function. Cardiac CT (CCT) ruled out coronary artery disease but showed a hypodense region (−80 HU), consistent with a fibro-adipose tissue infiltration, in left ventricular (LV) lateral wall with sub-epicardial distribution (Panel B and C, red arrows).