- Atherosclerotic plaque characterization by coronary computed tomography angiography (CCTA) enables quantification of coronary artery disease (CAD) burden and type, which has been demonstrated as the strongest discriminant of future risk of major adverse cardiac events (MACE). To date, there are no clinically useful thresholds to assist with understanding a patient's disease burden and guide diagnosis and management, as there exists with coronary artery calcium (CAC) scoring. The purpose of this manuscript is to establish clinically relevant plaque stages and thresholds based on evidence from invasive angiographic stenosis (ICA) and fractional flow reserve (FFR) data.
- Aim of the present study was to verify the feasibility and accuracy of live integration of myocardial fibrosis evaluated at CCT with EAM (electro-anatomical mapping).
- Large multicenter studies and meta-analysis have documented the diagnostic accuracy and the prognostic implications of stress echocardiography, cardiac magnetic resonance and, mainly, nuclear stress tests. However, none of them provides a comprehensive anatomical and functional evaluation within the same study as stress CT perfusion. Myocardial CT perfusion is the only non-invasive modality that allows to quantifying coronary stenosis and determining its functional relevance, constituting a potential “one-stop-shop” method for the diagnosis and global management of patients with known or suspected coronary artery disease.
- A 46-year-old man with an unremarkable past medical history and no cardiovascular risk factors was referred to perform cardiac magnetic resonance (CMR) for recent suspected myocarditis. CMR showed normal left ventricular volumes and systolic function, hypokinesis at the level of basal to mid inferolateral wall, and transmural late gadolinium enhancement with ischemic pattern was evident in the left circumflex artery territory at the basal and mid inferolateral wall (Fig. 1). To rule out the presence of obstructive coronary artery disease (CAD), an ECG-gated coronary computed tomography angiogram (CCTA) was performed, showing an anomalous origin of the circumflex coronary artery from the right coronary sinus with a retro-aortic course (Fig.
- We sought to evaluate the additional value of left atrial appendage (LAA) 3D printing derived from computed tomography (CCT) in determining the size for LAA occlusion (LAAO) devices as compared to standard measurement by using occurrence of LAA leak as endpoint.