Diagnostic concordance and discordance between angiography-based quantitative flow ratio and fractional flow reserve derived from computed tomography in complex coronary artery diseaseBoth quantitative flow ratio (QFR) and fractional flow reserve derived from computed tomography (FFRCT) have shown significant correlations with invasive wire-based fractional flow reserve. However, the correlation between QFR and FFRCT is not fully investigated in patients with complex coronary artery disease (CAD). The aim of this study is to investigate the correlation and agreement between QFR and FFRCT in patients with de novo three-vessel disease and/or left main CAD.
Live integration of comprehensive cardiac CT with electroanatomical mapping in patients with refractory ventricular tachycardiaAim of the present study was to verify the feasibility and accuracy of live integration of myocardial fibrosis evaluated at CCT with EAM (electro-anatomical mapping).
State-of-the-art-myocardial perfusion stress testing: Static CT perfusionLarge multicenter studies and meta-analysis have documented the diagnostic accuracy and the prognostic implications of stress echocardiography, cardiac magnetic resonance and, mainly, nuclear stress tests. However, none of them provides a comprehensive anatomical and functional evaluation within the same study as stress CT perfusion. Myocardial CT perfusion is the only non-invasive modality that allows to quantifying coronary stenosis and determining its functional relevance, constituting a potential “one-stop-shop” method for the diagnosis and global management of patients with known or suspected coronary artery disease.
Cardiovascular morbidity and mortality in patients with aortic valve calcification: A systematic review and meta-analysisAortic valve calcification (AVC) is an active process that involves inflammation, disorganization of matrix disposition, lipid accumulation and lamellar bone formation. AVC without hemodynamic changes has been associated with cardiovascular (CV) risk factors and increased risk of coronary and CV events. Nowadays, echocardiography is the standard imaging technique to evaluate aortic valve pathologies. However, cardiac computed tomography (CT) allows high accuracy and reproducible measurement of AVC, without exposing the patients to excessive radiation or contrast administration.
Submillisievert CT angiography for carotid arteries using wide array CT scanner and latest iterative reconstruction algorithm in comparison with previous generations technologies: Feasibility and diagnostic accuracyTo assess evaluability and diagnostic accuracy of a low dose CT angiography (CTA) protocol for carotid arteries using latest Iterative Reconstruction (IR) algorithm in comparison with standard 100 kVp protocol using previous generation CT and IR.
Left-dominant arrhythmogenic cardiomyopathy diagnosed at cardiac CTA 71 years-old man was referred to our Center after detection of a non-sustained ventricular tachycardia (NSVT) at ambulatory electrocardiogram (ECG) monitoring. His previous cardiological history was negative. Rest ECG showed negative T-waves on V4 V6 leads (Panel A). Blood examination was normal including high-sensitive troponin-I and C-reactive protein. Transthoracic echocardiography showed normal biventricular wall kinesis and function. Cardiac CT (CCT) ruled out coronary artery disease but showed a hypodense region (−80 HU), consistent with a fibro-adipose tissue infiltration, in left ventricular (LV) lateral wall with sub-epicardial distribution (Panel B and C, red arrows).