- The adoption of Computed tomography (CT)-defined sarcopenia to risk stratify transcatheter aortic valve implantation (TAVI) candidates remains limited by a lack of both standardized definition and evidence of independent value over currently adopted mortality prediction tools.
- TAVR is highly effective at reducing mortality of patients with severe aortic stenosis. However, despite the high rates of procedural success, some patients do not achieve a functional benefit or die within a short time period after the procedure. Pulmonary hypertension is a known predictor of poor outcome in patients undergoing TAVR and correlates strongly with PA enlargement measured on CT. Our study shows that MPA enlargement, defined as area-MPA ≥7.40 cm2 on pre-procedural CTA, is an independent predictor of 1-year mortality after TAVR. This imaging marker could be relevant in improving individual risk classification in TAVR candidates.
- Michael Morris: Consultant for Edwards Lifesciences. Educational training for Medtronic.
- Aortic valve calcification is supposed to be a possible cause of embolic stroke or subclinical valve thrombosis after transcatheter aortic valve replacement (TAVR). We aimed to assess the role of aortic valve calcification in the occurrence of in-hospital clinical complications and survival after TAVR.
- To investigate whether aortic valve calcification (AVC) scoring performed with different workstation platforms generates comparable and thus software-independent results.
- Global longitudinal strain (GLS) detects subclinical myocardial changes in patients with aortic stenosis (AS). Although GLS is typically measured by transthoracic echocardiography (TTE), assessment by multiphasic gated computed tomography angiography (CTA) has become recently available. We sought to evaluate the feasibility of CTA-derived GLS assessment and compare its agreement with TTE using the same post-processing software in severe AS patients undergoing transcatheter aortic valve replacement (TAVR) evaluation.